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Postbiotics

Heat-Treated Lactic Acid Bacteria

Strain

Raw Material (Strain)

1.    De-glu GLU70(GLU70)

2.    De-glu MB0601(MB0601) 

3. Dipro-rhamnosus(DS0508)

4.    Heat-treated strain MB201(ML-004)
5.    Heat-treated strain MB202(ML-036)
6.    Heat-treated strain MB203(ML-019) 
7.    Heat-treated strain MB204(ML-035)

Function

Function

1.    Gluten-degrading activity; Preventing, improving, or                 treating gliadin-induced inflammatory bowel disease               (Patented)

2.    Gluten-degrading activity (Patented)

3.    Obesity treatment and prevention

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Contains 17 kinds of amino acids and various organic acids and short-chain fatty acids

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De-glu MB1

Heat-treated and dried MB0601 strain with gluten-degrading activity

Equally effective as probiotics 

Prebiotic actions

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Enhanced stability

Versatility of application

De-glu MB1 dry powder

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De-glu MB2

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A composition for preventing, improving, or treating gliadin-induced inflammatory bowel disease comprising of heat-killed GLU70 as an active ingredient having gluten degradation

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Normal intestinal epithelial cell

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Intestinal epithelial cells damaged by gliadin

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Degeneration of damaged intestinal epithelial cells inhibited by De-glu MB2

Confirmed inhibition of gluten(gliadin)-induced degeneration of intestinal epithelial cells by De-glu MB2

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Decreased secretion of TNF-α (inflammatory cytokine)

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Increased secretion of IL-10 
(anti-inflammatory cytokine)

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Decreased expression levels of inflammatory
proteins in De-glu GLU70-ingested groups

Reduced secretion of inflammatory cytokines, increased secretion of anti-inflammatory cytokines, and decreased expression of inflammatory proteins by De-glu MB2 strain 

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Dipro-rhamnosus heat-treated strain

Animal Model Experiment (In vivo test)

  • To test the weight gain inhibition effect by the novel strain, high fat diet-induced obese mice were administered the strain or the culture medium for 12 weeks

  • Confirmed the weight gain inhibition effect of 5.7% compared to the negative control

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Heat-treated strains MB201~204

Organic Acid & Amino Acid Content Test Report

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Certificate of Deposit 

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